GPA33 (NM_005814) Human Recombinant Protein
Product Specifications
Background
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]
Synonyms
A33
Gene ID
10223
UniProt
Q99795
Accession Number mRNA
NM_005814
Chromosomal Location
1q24.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea
Function
Druggable Genome, Transmembrane
Molecular Weight
31.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GPA33
Species
Human
Protein ID
NP_005805
Overview
Purified recombinant protein of Human glycoprotein A33 (transmembrane) (GPA33), Ile22-Val235-GGGGS-Tyr257-End, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10223
Uniprot URL
https://www.uniprot.org/uniprot/Q99795
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005814
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005805
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