CSNK1G1 (NM_022048) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE) . [provided by RefSeq, Jul 2016]

Overview

Purified recombinant protein of Human casein kinase 1, gamma 1 (CSNK1G1), Arg163-End, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

CK1gamma1

Gene ID

53944

UniProt

Q9HCP0, A0A024R5W3

Accession Number mRNA

NM_022048

Chromosomal Location

15q22.31

Expression System

E. coli

Tag

N-His

Related Pathways

Hedgehog signaling pathway

Field of Research

Hedgehog signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

>80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea

Function

Druggable Genome, Protein Kinase

Molecular Weight

30.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.