HMG1 (HMGB1) (NM_002128) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
Overview
Purified recombinant protein of Human high mobility group box 1 (HMGB1), full length, with N-terminal His tag, expressed in E.coli, 50ug
Synonyms
HMG-1; HMG1; HMG3; SBP-1
Gene ID
3146
UniProt
P09429, A0A024RDR0, Q5T7C3
Accession Number mRNA
NM_002128
Chromosomal Location
13q12.3
Expression System
E. coli
Tag
N-His
Related Pathways
Base excision repair
Field of Research
Base excision repair
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
>80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea
Function
Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Molecular Weight
24.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HMGB1
Species
Human
Protein ID
NP_002119
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3146
Uniprot URL
https://www.uniprot.org/uniprot/P09429
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002128
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002119
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