Lsm6 (NM_030145) Mouse Recombinant Protein
Product Specifications
Background
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) . The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.[UniProtKB/Swiss-Prot Function]
Synonyms
1500031N17Rik; 2410088K19Rik; AI747288
Gene ID
78651
UniProt
P62313, Q542U7
Accession Number mRNA
NM_030145
Chromosomal Location
8 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
9.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Lsm6
Species
Mouse
Protein ID
NP_084421
Overview
Purified recombinant protein of Mouse LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/78651
Uniprot URL
https://www.uniprot.org/uniprot/P62313
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030145
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_084421
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