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Timm8a1 (NM_013898) Mouse Recombinant Protein

Product Specifications

Background

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse translocase of inner mitochondrial membrane 8A1 (Timm8a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Ddp1; DXHXS1274E; Fci-12; Tim8a; Timm8a

Gene ID

30058

UniProt

Q9WVA2

Accession Number mRNA

NM_013898

Chromosomal Location

X 56.18 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

11.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Timm8a1

Species

Mouse

Protein ID

NP_038926

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/30058

Uniprot URL

https://www.uniprot.org/uniprot/Q9WVA2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_013898

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_038926

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