Eif4ebp3 (NM_201256) Mouse Recombinant Protein
Product Specifications
Background
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse eukaryotic translation initiation factor 4E binding protein 3 (Eif4ebp3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
4e-bp3
Gene ID
108112
UniProt
Q80VV3
Accession Number mRNA
NM_201256
Chromosomal Location
18 B2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
11.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Eif4ebp3
Species
Mouse
Protein ID
NP_957708
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/108112
Uniprot URL
https://www.uniprot.org/uniprot/Q80VV3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_201256
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_957708
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