Guca2b (NM_008191) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of the guanylin family and preproprotein that is proteolytically processed to generate a mature protein product. The mature protein product, known as uroguanylin, is an endogenous ligand for the guanylate cyclase-C receptor and may regulate salt and water homeostasis in the intestine and kidneys. Homozygous knockout mice for this gene exhibit impaired sodium chloride excretion and elevated arterial pressure. This gene is present in a gene cluster with a related guanylin family member on chromosome 4. [provided by RefSeq, Sep 2015]
Overview
Purified recombinant protein of Mouse guanylate cyclase activator 2b (retina) (Guca2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AV066530; Gca; Gcap2; Ugn; urog
Gene ID
14916
UniProt
O09051, Q9QUQ3
Accession Number mRNA
NM_008191
Chromosomal Location
4 55.48 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
11.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Guca2b
Species
Mouse
Protein ID
NP_032217
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14916
Uniprot URL
https://www.uniprot.org/uniprot/O09051
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008191
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032217
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