Pclaf (NM_026515) Mouse Recombinant Protein
Selected Variant
PM49054M5
Size: 20 µg
Product Specifications
Background
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse PCNA clamp associated factor (Pclaf), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2810417H13Rik; AA409629; mKIAA0101; Ns5apt9; Ns5atp9; p15 (PAF) ; Paf; PAF15
Gene ID
68026
UniProt
Q9CQX4
Accession Number mRNA
NM_026515
Chromosomal Location
9 C
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
12 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pclaf
Species
Mouse
Protein ID
NP_080791
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68026
Uniprot URL
https://www.uniprot.org/uniprot/Q9CQX4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_026515
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080791
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