Phlda3 (NM_013750) Mouse Recombinant Protein
Product Specifications
Background
P53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
Tih1
Gene ID
27280
UniProt
Q9WV95
Accession Number mRNA
NM_013750
Chromosomal Location
1 59.26 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
13.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Phlda3
Species
Mouse
Protein ID
NP_038778
Overview
Purified recombinant protein of Mouse pleckstrin homology like domain, family A, member 3 (Phlda3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27280
Uniprot URL
https://www.uniprot.org/uniprot/Q9WV95
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013750
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_038778
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