Cby1 (NM_028634) Mouse Recombinant Protein
Product Specifications
Background
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse chibby family member 1, beta catenin antagonist (Cby1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110014P06Rik; arb1; CBY; Pgea1; PGEA14
Gene ID
73739
UniProt
Q9D1C2
Accession Number mRNA
NM_028634
Chromosomal Location
15
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
14.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cby1
Species
Mouse
Protein ID
NP_082910
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/73739
Uniprot URL
https://www.uniprot.org/uniprot/Q9D1C2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_028634
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_082910
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