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Cby1 (NM_028634) Mouse Recombinant Protein

Product Specifications

Background

Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse chibby family member 1, beta catenin antagonist (Cby1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1110014P06Rik; arb1; CBY; Pgea1; PGEA14

Gene ID

73739

UniProt

Q9D1C2

Accession Number mRNA

NM_028634

Chromosomal Location

15

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

14.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Cby1

Species

Mouse

Protein ID

NP_082910

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/73739

Uniprot URL

https://www.uniprot.org/uniprot/Q9D1C2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_028634

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_082910

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