Ppp1r11 (NM_029632) Mouse Recombinant Protein
Selected Variant
PM48924M5
Size: 20 µg
Product Specifications
Background
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901) . Inhibitor of protein phosphatase 1 (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse protein phosphatase 1, regulatory inhibitor subunit 11 (Ppp1r11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1500041B02Rik; AV117883; Hcgv; Tcte5; Tctex-5; Tctex5
Gene ID
76497
UniProt
Q8K1L5, A5A4Y9
Accession Number mRNA
NM_029632
Chromosomal Location
17 19.16 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
14.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ppp1r11
Species
Mouse
Protein ID
NP_083908
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/76497
Uniprot URL
https://www.uniprot.org/uniprot/Q8K1L5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_029632
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_083908
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