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Pfn1 (NM_011072) Mouse Recombinant Protein

Product Specifications

Background

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse profilin 1 (Pfn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Pfn

Gene ID

18643

UniProt

P62962, Q5SX50, Q3U7V7

Accession Number mRNA

NM_011072

Chromosomal Location

11 43.21 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

15 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Pfn1

Species

Mouse

Protein ID

NP_035202

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/18643

Uniprot URL

https://www.uniprot.org/uniprot/P62962

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_011072

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_035202

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