Pfn1 (NM_011072) Mouse Recombinant Protein
Product Specifications
Background
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse profilin 1 (Pfn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Pfn
Gene ID
18643
UniProt
P62962, Q5SX50, Q3U7V7
Accession Number mRNA
NM_011072
Chromosomal Location
11 43.21 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
15 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pfn1
Species
Mouse
Protein ID
NP_035202
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18643
Uniprot URL
https://www.uniprot.org/uniprot/P62962
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011072
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035202
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