Pla2g2a (NM_001082531) Mouse Recombinant Protein
Selected Variant
PM48834M5
Size: 20 µg
Product Specifications
Background
Proteins belonging to the phospholipase A2 (PLA2) family hydrolyze phospholipids into sn2 fatty acids and lysophospholipids. They function in a variety of cellular processes, including the digestion of phospholipids and the production of molecules that induce inflammatory responses. This gene encodes a member of the group II class of secretory PLA2s. The secreted enzyme binds to heparin on the cell surface. Mutations in this gene increase the occurrence of intestinal polyps caused by a dominant mutation in the adenomatosis polyposis coli gene. A frameshift inactivates this gene product in some mouse strains including the strain of the reference genome, C57BL/6J, whereas a functional protein is produced in other strains. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Mouse phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), transcript variant 1, coding, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
EF; Mom1; Pla2; sPLA2; sPla2-IIA
Gene ID
18780
UniProt
P31482, V5TDK8
Accession Number mRNA
NM_001082531
Chromosomal Location
4 70.57 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
16.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pla2g2a
Species
Mouse
Protein ID
NP_001076000
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18780
Uniprot URL
https://www.uniprot.org/uniprot/P31482
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001082531
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001076000
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