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Pla2g2a (NM_001082531) Mouse Recombinant Protein

Selected Variant

PM48834M5

Size: 20 µg

Product Specifications

Background

Proteins belonging to the phospholipase A2 (PLA2) family hydrolyze phospholipids into sn2 fatty acids and lysophospholipids. They function in a variety of cellular processes, including the digestion of phospholipids and the production of molecules that induce inflammatory responses. This gene encodes a member of the group II class of secretory PLA2s. The secreted enzyme binds to heparin on the cell surface. Mutations in this gene increase the occurrence of intestinal polyps caused by a dominant mutation in the adenomatosis polyposis coli gene. A frameshift inactivates this gene product in some mouse strains including the strain of the reference genome, C57BL/6J, whereas a functional protein is produced in other strains. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Mouse phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), transcript variant 1, coding, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

EF; Mom1; Pla2; sPLA2; sPla2-IIA

Gene ID

18780

UniProt

P31482, V5TDK8

Accession Number mRNA

NM_001082531

Chromosomal Location

4 70.57 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

16.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Pla2g2a

Species

Mouse

Protein ID

NP_001076000

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/18780

Uniprot URL

https://www.uniprot.org/uniprot/P31482

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001082531

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001076000

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