Pde6d (NM_008801) Mouse Recombinant Protein
Product Specifications
Background
Promotes the release of prenylated target proteins from cellular membranes (PubMed:22179043) . Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22179043) . Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity) . Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (PubMed:22179043) . Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.[UniProtKB/Swiss-Prot Function]
Synonyms
AI841218; PrBP/delta
Gene ID
18582
UniProt
O55057, Q3TDQ8
Accession Number mRNA
NM_008801
Chromosomal Location
1 C5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
17.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pde6d
Species
Mouse
Protein ID
NP_032827
Overview
Purified recombinant protein of Mouse phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18582
Uniprot URL
https://www.uniprot.org/uniprot/O55057
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008801
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032827
Curated Selection
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