Pde6d (NM_008801) Mouse Recombinant Protein

Product Specifications

Background

Promotes the release of prenylated target proteins from cellular membranes (PubMed:22179043) . Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22179043) . Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity) . Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (PubMed:22179043) . Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI841218; PrBP/delta

Gene ID

18582

UniProt

O55057, Q3TDQ8

Accession Number mRNA

NM_008801

Chromosomal Location

1 C5

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

17.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.