Cplx3 (NM_146223) Mouse Recombinant Protein
Product Specifications
Background
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (PubMed:19386896) . Required for the maintenance of synaptic ultrastructure in the adult retina (PubMed:19386896) . Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (PubMed:15911881, PubMed:19386896, PubMed:27335398) . Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca (2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca (2+) vesicle release (PubMed:22694764, PubMed:27335398) .[UniProtKB/Swiss-Prot Function]
Synonyms
BC016632; CpxIII; ERGIC-53L; ERGL; Lamn1l; Lman1l
Gene ID
235415
UniProt
Q8R1B5
Accession Number mRNA
NM_146223
Chromosomal Location
9 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
17.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cplx3
Species
Mouse
Protein ID
NP_666335
Overview
Purified recombinant protein of Mouse complexin 3 (Cplx3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/235415
Uniprot URL
https://www.uniprot.org/uniprot/Q8R1B5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_146223
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_666335
Curated Selection
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