Ly6h (NM_001135689) Mouse Recombinant Protein

Product Specifications

Background

Believed to act as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response (PubMed:26276394) . May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface (PubMed:25716842) . Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse lymphocyte antigen 6 complex, locus H (Ly6h), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID

23934

UniProt

Q9WUC3, Q8K356, Q544M1

Accession Number mRNA

NM_001135689

Chromosomal Location

15 D3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

17 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.