Cep19 (NM_025892) Mouse Recombinant Protein
Product Specifications
Background
Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes.[UniProtKB/Swiss-Prot Function]
Synonyms
1500031L02Rik; AI428934; AL022620
Gene ID
66994
UniProt
Q9CQA8
Accession Number mRNA
NM_025892
Chromosomal Location
16 B2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
19.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cep19
Species
Mouse
Protein ID
NP_080168
Overview
Purified recombinant protein of Mouse centrosomal protein 19 (Cep19), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66994
Uniprot URL
https://www.uniprot.org/uniprot/Q9CQA8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025892
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080168
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