Cfl2 (NM_007688) Mouse Recombinant Protein
Product Specifications
Background
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere.[UniProtKB/Swiss-Prot Function]
Gene ID
12632
UniProt
P45591, Q3UHW9
Accession Number mRNA
NM_007688
Chromosomal Location
12 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
18.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cfl2
Species
Mouse
Protein ID
NP_031714
Overview
Purified recombinant protein of Mouse cofilin 2, muscle (Cfl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12632
Uniprot URL
https://www.uniprot.org/uniprot/P45591
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007688
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031714
Curated Selection
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