Cfl2 (NM_007688) Mouse Recombinant Protein

Product Specifications

Background

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse cofilin 2, muscle (Cfl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID

12632

UniProt

P45591, Q3UHW9

Accession Number mRNA

NM_007688

Chromosomal Location

12 C1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

18.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.