Nudt3 (NM_019837) Mouse Recombinant Protein
Product Specifications
Background
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphosphate) is not a substrate. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate (By similarity) . Acts as a negative regulator of the ERK1/2 pathway.[UniProtKB/Swiss-Prot Function]
Synonyms
1110011B09Rik; AA960325; Dipp; Dipp1
Gene ID
56409
UniProt
Q9JI46
Accession Number mRNA
NM_019837
Chromosomal Location
17 A3.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
19 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nudt3
Species
Mouse
Protein ID
NP_062811
Overview
Purified recombinant protein of Mouse nudix (nucleotide diphosphate linked moiety X) -type motif 3 (Nudt3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56409
Uniprot URL
https://www.uniprot.org/uniprot/Q9JI46
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019837
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062811
Curated Selection
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