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Ppp1r1a (NM_021391) Mouse Recombinant Protein

Product Specifications

Background

Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B) . Does not inhibit type-2 phosphatases.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse protein phosphatase 1, regulatory inhibitor subunit 1A (Ppp1r1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

0610038N18Rik; I-1

Gene ID

58200

UniProt

Q9ERT9

Accession Number mRNA

NM_021391

Chromosomal Location

15 F3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

18.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ppp1r1a

Species

Mouse

Protein ID

NP_067366

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/58200

Uniprot URL

https://www.uniprot.org/uniprot/Q9ERT9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021391

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_067366

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