Cirbp (NM_007705) Mouse Recombinant Protein
Selected Variant
PM48621M5
Size: 20 µg
Product Specifications
Background
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse cold inducible RNA binding protein (Cirbp), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Cirp; R74941
Gene ID
12696
UniProt
P60824
Accession Number mRNA
NM_007705
Chromosomal Location
10 39.72 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
18.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cirbp
Species
Mouse
Protein ID
NP_031731
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12696
Uniprot URL
https://www.uniprot.org/uniprot/P60824
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007705
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031731
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