Arf6 (NM_007481) Mouse Recombinant Protein
Product Specifications
Background
GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (PubMed:11950392) . Required for normal completion of mitotic cytokinesis. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface levels of adherens junction proteins such as CDH1 (PubMed:29420262, PubMed:20080746) . Required for NTRK1 sorting to the recycling pathway from early endosomes (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
AI788669; AW496366
Gene ID
11845
UniProt
P62331, Q3U0D7
Accession Number mRNA
NM_007481
Chromosomal Location
12 C2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
20.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Arf6
Species
Mouse
Protein ID
NP_031507
Overview
Purified recombinant protein of Mouse ADP-ribosylation factor 6 (Arf6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11845
Uniprot URL
https://www.uniprot.org/uniprot/P62331
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007481
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031507
Curated Selection
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