Yaf2 (NM_024189) Mouse Recombinant Protein
Product Specifications
Background
Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.[UniProtKB/Swiss-Prot Function]
Synonyms
2810021M11Rik
Gene ID
67057
UniProt
Q99LW6
Accession Number mRNA
NM_024189
Chromosomal Location
15 E3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
19.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Yaf2
Species
Mouse
Protein ID
NP_077151
Overview
Purified recombinant protein of Mouse YY1 associated factor 2 (Yaf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67057
Uniprot URL
https://www.uniprot.org/uniprot/Q99LW6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024189
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_077151
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