Dhps (BC039963) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.[UniProtKB/Swiss-Prot Function]
Synonyms
Dhs, MGC49129, MGC74384
Gene ID
330817
UniProt
Q3TXU5
Accession Number mRNA
BC039963
Chromosomal Location
8 C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
20.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dhps
Species
Mouse
Overview
Purified recombinant protein of Mouse deoxyhypusine synthase (cDNA clone MGC:49129 IMAGE:4240646), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/330817
Uniprot URL
https://www.uniprot.org/uniprot/Q3TXU5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC039963
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