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Dhps (BC039963) Mouse Recombinant Protein

Product Specifications

Background

Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse deoxyhypusine synthase (cDNA clone MGC:49129 IMAGE:4240646), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Dhs, MGC49129, MGC74384

Gene ID

330817

UniProt

Q3TXU5

Accession Number mRNA

BC039963

Chromosomal Location

8 C3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

20.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Dhps

Species

Mouse

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/330817

Uniprot URL

https://www.uniprot.org/uniprot/Q3TXU5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/BC039963

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