Tmco1 (NM_001039483) Mouse Recombinant Protein

Product Specifications

Background

Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis (PubMed:27212239) . In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store (PubMed:27212239) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse transmembrane and coiled-coil domains 1 (Tmco1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1190006A08Rik; 4930403O06Rik; AA109065; AU022572; ESTM39

Gene ID

68944

UniProt

Q921L3, Q3V4A0

Accession Number mRNA

NM_001039483

Chromosomal Location

1 H2.3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

21.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.