Tmco1 (NM_001039483) Mouse Recombinant Protein
Product Specifications
Background
Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis (PubMed:27212239) . In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store (PubMed:27212239) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse transmembrane and coiled-coil domains 1 (Tmco1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1190006A08Rik; 4930403O06Rik; AA109065; AU022572; ESTM39
Gene ID
68944
UniProt
Q921L3, Q3V4A0
Accession Number mRNA
NM_001039483
Chromosomal Location
1 H2.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
21.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tmco1
Species
Mouse
Protein ID
NP_001034572
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68944
Uniprot URL
https://www.uniprot.org/uniprot/Q921L3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001039483
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001034572
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