Kras (NM_021284) Mouse Recombinant Protein
Selected Variant
PM48480M5
Size: 20 µg
Product Specifications
Background
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity) . Plays an important role in the regulation of cell proliferation (PubMed:6474169, PubMed:1352876) . Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Kirsten rat sarcoma viral oncogene homolog (Kras), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI929937; c-K-ras; c-Ki-ras; K-Ras; K-ras; Ki-ras; Kras-2; Kras2; p21B; ras
Gene ID
16653
UniProt
P32883, Q5J7N1
Accession Number mRNA
NM_021284
Chromosomal Location
6 77.37 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
21.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Kras
Species
Mouse
Protein ID
NP_067259
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16653
Uniprot URL
https://www.uniprot.org/uniprot/P32883
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021284
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_067259
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