Ncs1 (NM_019681) Mouse Recombinant Protein
Product Specifications
Background
Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity) . Stimulates PI4KB kinase activity (By similarity) . Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity) . May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
9430075O15Rik; A730032G13Rik; AI836659; Freq; Mfreq; NCS-1
Gene ID
14299
UniProt
Q8BNY6
Accession Number mRNA
NM_019681
Chromosomal Location
2 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
21.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ncs1
Species
Mouse
Protein ID
NP_062655
Overview
Purified recombinant protein of Mouse neuronal calcium sensor 1 (Ncs1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14299
Uniprot URL
https://www.uniprot.org/uniprot/Q8BNY6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019681
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062655
Curated Selection
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