Ncs1 (NM_019681) Mouse Recombinant Protein

Product Specifications

Background

Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity) . Stimulates PI4KB kinase activity (By similarity) . Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity) . May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse neuronal calcium sensor 1 (Ncs1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

9430075O15Rik; A730032G13Rik; AI836659; Freq; Mfreq; NCS-1

Gene ID

14299

UniProt

Q8BNY6

Accession Number mRNA

NM_019681

Chromosomal Location

2 B

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

21.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.