Nkiras1 (NM_023526) Mouse Recombinant Protein
Product Specifications
Background
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
2400004O09Rik; kappaB-Ras1; KBRAS1
Gene ID
69721
UniProt
Q8CEC5
Accession Number mRNA
NM_023526
Chromosomal Location
14 A1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
21.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nkiras1
Species
Mouse
Protein ID
NP_076015
Overview
Purified recombinant protein of Mouse NFKB inhibitor interacting Ras-like protein 1 (Nkiras1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/69721
Uniprot URL
https://www.uniprot.org/uniprot/Q8CEC5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023526
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_076015
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