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Hikeshi (NM_026304) Mouse Recombinant Protein

Product Specifications

Background

Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity) . May also be indirectly required for organization and/or function of the secretory apparatus in Clara cells in lung.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse heat shock protein nuclear import factor (Hikeshi), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

0610007P06Rik; 1110002N09Rik; l (7) 6Rn; l7Rn6

Gene ID

67669

UniProt

Q9DD02

Accession Number mRNA

NM_026304

Chromosomal Location

7 50.4 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

21.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Hikeshi

Species

Mouse

Protein ID

NP_080580

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/67669

Uniprot URL

https://www.uniprot.org/uniprot/Q9DD02

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_026304

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_080580

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