Prdx1 (NM_011034) Mouse Recombinant Protein
Product Specifications
Background
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H (2) O (2) (By similarity) . Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (PubMed:19766572) .[UniProtKB/Swiss-Prot Function]
Synonyms
MSP23; NkefA; OSF-3; OSF3; PAG; Paga; PrdxI; prx1; PrxI; Tdpx2; TDX2; TPxA
Gene ID
18477
UniProt
P35700
Accession Number mRNA
NM_011034
Chromosomal Location
4 53.28 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
22.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Prdx1
Species
Mouse
Protein ID
NP_035164
Overview
Purified recombinant protein of Mouse peroxiredoxin 1 (Prdx1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18477
Uniprot URL
https://www.uniprot.org/uniprot/P35700
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011034
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035164
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