Arl6ip1 (NM_019419) Mouse Recombinant Protein
Product Specifications
Background
Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity-dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport (PubMed:18684713) . Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9) . Inhibits cleavage of CASP9-dependent substrates and downstream markers of apoptosis but not CASP9 itself. May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
Aip-1; AIP-6; AL022945; Arl6ip; ARMER; AU042858; C85138; mKIAA0069
Gene ID
54208
UniProt
Q9JKW0, Q80ZW9
Accession Number mRNA
NM_019419
Chromosomal Location
7 F1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
23.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Arl6ip1
Species
Mouse
Protein ID
NP_062292
Overview
Purified recombinant protein of Mouse ADP-ribosylation factor-like 6 interacting protein 1 (Arl6ip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54208
Uniprot URL
https://www.uniprot.org/uniprot/Q9JKW0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019419
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062292
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