Fadd (NM_010175) Mouse Recombinant Protein

Product Specifications

Background

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity) . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse Fas (TNFRSF6) -associated via death domain (Fadd), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Mort1/FADD

Gene ID

14082

UniProt

Q61160

Accession Number mRNA

NM_010175

Chromosomal Location

7 88.85 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

23 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.