Fadd (NM_010175) Mouse Recombinant Protein
Product Specifications
Background
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity) . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
Mort1/FADD
Gene ID
14082
UniProt
Q61160
Accession Number mRNA
NM_010175
Chromosomal Location
7 88.85 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
23 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Fadd
Species
Mouse
Protein ID
NP_034305
Overview
Purified recombinant protein of Mouse Fas (TNFRSF6) -associated via death domain (Fadd), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14082
Uniprot URL
https://www.uniprot.org/uniprot/Q61160
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010175
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034305
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