Cmtm4 (NM_153582) Mouse Recombinant Protein
Product Specifications
Background
Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse CKLF-like MARVEL transmembrane domain containing 4 (Cmtm4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Cklfsf4; D19397; ENSMUSG00000051554; Gm9853
Gene ID
97487
UniProt
Q8CJ61
Accession Number mRNA
NM_153582
Chromosomal Location
8 D3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
22.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cmtm4
Species
Mouse
Protein ID
NP_705810
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/97487
Uniprot URL
https://www.uniprot.org/uniprot/Q8CJ61
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_153582
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_705810
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