Mpzl1 (NM_001001880) Mouse Recombinant Protein
Product Specifications
Background
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 2 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2, may be involved in regulation of integrin-mediated cell motility (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse myelin protein zero-like 1 (Mpzl1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110007A10Rik; PZR
Gene ID
68481
UniProt
Q3TEW6, A0A0R4J0V2
Accession Number mRNA
NM_001001880
Chromosomal Location
1 H2.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
23 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mpzl1
Species
Mouse
Protein ID
NP_001001880
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68481
Uniprot URL
https://www.uniprot.org/uniprot/Q3TEW6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001001880
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001001880
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