Tesc (NM_021344) Mouse Recombinant Protein
Product Specifications
Background
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na (+) /H (+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse tescalcin (Tesc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1010001A17Rik; 2410011K10Rik; TE-1
Gene ID
57816
UniProt
Q9JKL5, D0EM45
Accession Number mRNA
NM_021344
Chromosomal Location
5 57.84 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
24.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tesc
Species
Mouse
Protein ID
NP_067319
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57816
Uniprot URL
https://www.uniprot.org/uniprot/Q9JKL5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021344
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_067319
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