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Scn3b (NM_153522) Mouse Recombinant Protein

Product Specifications

Background

Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 1, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1110001K16Rik; 4833414B02Rik; Scnb3

Gene ID

235281

UniProt

Q8BHK2

Accession Number mRNA

NM_153522

Chromosomal Location

9 A5.1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

24.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Scn3b

Species

Mouse

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/235281

Uniprot URL

https://www.uniprot.org/uniprot/Q8BHK2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_153522

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