Gid4 (NM_025757) Mouse Recombinant Protein
Product Specifications
Background
Substrate-recognition subunit of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Binds proteins and peptides with a Pro/N-degron consisting of an unmodified N-terminal Pro followed by a small residue, and has the highest affinity for the peptide Pro-Gly-Leu-Trp. Binds peptides with an N-terminal sequence of the type Pro-[Ala, Gly]-[Leu, Met, Gln, Ser, Tyr]-[Glu, Gly, His, Ser, Val, Trp, Tyr]. Does not bind peptides with an acetylated N-terminal Pro residue.[UniProtKB/Swiss-Prot Function]
Synonyms
4933439F18Rik
Gene ID
66771
UniProt
Q9CPY6
Accession Number mRNA
NM_025757
Chromosomal Location
11 B2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
24.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gid4
Species
Mouse
Protein ID
NP_080033
Overview
Purified recombinant protein of Mouse GID complex subunit 4, VID24 homolog (Gid4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66771
Uniprot URL
https://www.uniprot.org/uniprot/Q9CPY6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025757
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080033
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