Gadd45gip1 (NM_183358) Mouse Recombinant Protein
Product Specifications
Background
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.[UniProtKB/Swiss-Prot Function]
Synonyms
2310040G17Rik; AI425883; Crif1; MRP-L59; Plinp1
Gene ID
102060
UniProt
Q9CR59
Accession Number mRNA
NM_183358
Chromosomal Location
8 C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
26.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gadd45gip1
Species
Mouse
Protein ID
NP_899202
Overview
Purified recombinant protein of Mouse growth arrest and DNA-damage-inducible, gamma interacting protein 1 (Gadd45gip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/102060
Uniprot URL
https://www.uniprot.org/uniprot/Q9CR59
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_183358
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_899202
Curated Selection
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