Rab21 (NM_024454) Mouse Recombinant Protein
Product Specifications
Background
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (PubMed:16754960) . As a result, may regulate cell adhesion and migration (PubMed:16754960) . During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (PubMed:18804435) . Involved in neurite growth (By similarity) . Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse RAB21, member RAS oncogene family (Rab21), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
9630024B22
Gene ID
216344
UniProt
P35282, Q0PD35
Accession Number mRNA
NM_024454
Chromosomal Location
10 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
24.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rab21
Species
Mouse
Protein ID
NP_077774
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/216344
Uniprot URL
https://www.uniprot.org/uniprot/P35282
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024454
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_077774
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