Styx (NM_019637) Mouse Recombinant Protein
Product Specifications
Background
Catalytically inactive phosphatase (PubMed:7592916) . Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) (By similarity) . Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2) (By similarity) . By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates (By similarity) . Plays a role in spermatogenesis (PubMed:11842224) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse serine/threonine/tyrosine interaction protein (Styx), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
0610039A20Rik; hStyxb
Gene ID
56291
UniProt
Q60969
Accession Number mRNA
NM_019637
Chromosomal Location
14 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
25.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Styx
Species
Mouse
Protein ID
NP_062611
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56291
Uniprot URL
https://www.uniprot.org/uniprot/Q60969
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019637
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062611
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