Commd5 (NM_025536) Mouse Recombinant Protein
Selected Variant
PM48100M5
Size: 20 µg
Product Specifications
Background
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse COMM domain containing 5 (Commd5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2310065H03Rik; AI854466; D15Ertd81e; Hcarg
Gene ID
66398
UniProt
Q8R395, A0A0R4J0U7
Accession Number mRNA
NM_025536
Chromosomal Location
15 36.28 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
24.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Commd5
Species
Mouse
Protein ID
NP_079812
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66398
Uniprot URL
https://www.uniprot.org/uniprot/Q8R395
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025536
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079812
Price
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