Gid8 (NM_029607) Mouse Recombinant Protein
Selected Variant
PM48064M5
Size: 20 µg
Product Specifications
Background
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse GID complex subunit 8 (Gid8), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2310003C23Rik; 4833420G11Rik; AI451474; Twa1
Gene ID
76425
UniProt
Q9D7M1
Accession Number mRNA
NM_029607
Chromosomal Location
2 H4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
26.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gid8
Species
Mouse
Protein ID
NP_083883
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/76425
Uniprot URL
https://www.uniprot.org/uniprot/Q9D7M1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_029607
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_083883
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