Rnf114 (NM_030743) Mouse Recombinant Protein
Selected Variant
PM48056M5
Size: 20 µg
Product Specifications
Background
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse ring finger protein 114 (Rnf114), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110008J21Rik; AI225886; AW549494; Zfp228; Zfp313; Znf228
Gene ID
81018
UniProt
Q9ET26
Accession Number mRNA
NM_030743
Chromosomal Location
2 H3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
26.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rnf114
Species
Mouse
Protein ID
NP_109668
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/81018
Uniprot URL
https://www.uniprot.org/uniprot/Q9ET26
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030743
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_109668
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