Diablo (NM_023232) Mouse Recombinant Protein
Product Specifications
Background
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP) . Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse diablo, IAP-binding mitochondrial protein (Diablo), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
0610041G12Rik; 1700006L01Rik; AU040403; Smac
Gene ID
66593
UniProt
Q9JIQ3
Accession Number mRNA
NM_023232
Chromosomal Location
5 F
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
26.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Diablo
Species
Mouse
Protein ID
NP_075721
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66593
Uniprot URL
https://www.uniprot.org/uniprot/Q9JIQ3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023232
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075721
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