Apip (NM_019735) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) . Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse APAF1 interacting protein (Apip), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
APIP2; CGI-29; Mmrp19
Gene ID
56369
UniProt
Q9WVQ5
Accession Number mRNA
NM_019735
Chromosomal Location
2 E2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
26.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Apip
Species
Mouse
Protein ID
NP_062709
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56369
Uniprot URL
https://www.uniprot.org/uniprot/Q9WVQ5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019735
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062709
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